The Function of Secondary Argonautes in the ALG-3/4 Sperm Small RNA pathway in C. elegans

Scientists have identified a total of 24 argonautes in C. elegans. However, there is still uncertainty as to the specific function of some of these worm-specific argonautes and the question remains as to which secondary argonautes are involved in the ALG-3/4 pathway and can the method for how they regulate their targets be uncovered. From male and sperm gene expression datasets, we have identified candidate secondary Argonautes that could be involved in the downstream function of the ALG-3/4 pathway (Unpublished data, Mello Lab). Here we report that the addition of the genetic mutants wago-1, wago-9, and wago-10 produce significantly lower broods and their compounded effect can be seen in the overall phenotype of the worm

Unwanted False Alarms (BCA Classifications 2 & 3)

The Australasian Fire Authorities Council (AFAC) applies an integrated approach to emergency service operations in Australia and New Zealand. With recent increases in unwanted false alarms, AFAC identified kitchen exhaust systems as a potential solution to reduce unwanted false alarms in residential buildings. Our team conducted a cost-benefit analysis on installing kitchen exhaust systems and determined it is cost-effective to install local exhaust in low-rise but not high-rise buildings. Through our findings, we recommend investigation into alternative solutions